What question did this study set out to answer?

To assess the feasibility of visualizing the left atrial appendage and detecting thrombi using live three-dimensional echocardiography compared to two-dimensional and transesophageal echocardiography.

January 3, 2006Echocardiography

Assessment of Left Atrial Appendage by Live Three‐Dimensional Echocardiography: Early Experience and Comparison with Transesophageal Echocardiography

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Why the study?

Does Live Three-Dimensional Echocardiography (L3D) improve visualization of the left atrial appendage compared to 2D echocardiography in patients referred for routine echocardiography?

Population

204 consecutive patients referred for routine 2D or transesophageal echocardiography (TEE)

Comparison

Live Three-Dimensional Echocardiography (L3D) vs Transthoracic echocardiography and…

Design

Cross-sectional

Authors

IAIldiko AgostonThe University of Texas Health Science Center at San Antonio TXTianrong XieThe University of Texas Medical Branch at Galveston FTFrank TillerThe University of Texas Medical Branch at Galveston

Discussion

Member takes

Implication

L3D may improve LAA visualization in routine echocardiography; hypothesis-generating for thrombus detection, should not yet change practice.

Key Points

To assess the feasibility of visualizing the left atrial appendage and detecting thrombi using live three-dimensional echocardiography compared to two-dimensional and transesophageal echocardiography.
Evaluated 204 consecutive patients referred for routine two-dimensional transthoracic echocardiography (2D) or transesophageal echocardiography (TEE).
Acquired wide-angled live three-dimensional echocardiography (L3D) views from parasternal and apical windows using a specialized 4D cardiac reconstruction platform.
Compared L3D visualization rates to 2D echocardiography across all subjects and evaluated thrombus detection accuracy against TEE in a 37-patient subgroup.
L3D adequately visualized the left atrial appendage in 68.1% (139/204) of patients compared to 45.5% (93/204) with 2D echocardiography (P < 0.0001).
In patients with diagnostic image quality (n=104), L3D achieved 100% (104/104) visualization of the left atrial appendage compared to 74% (77/104) with 2D echocardiography (P < 0.0001).
Among 37 patients undergoing TEE, L3D provided diagnostic visualization in 34 patients and successfully identified left atrial appendage thrombi in all 8 patients confirmed by TEE.

Structured PICO

Does Live Three-Dimensional Echocardiography (L3D) improve visualization of the left atrial appendage compared to 2D echocardiography in patients referred for routine echocardiography?

Population

204 consecutive patients referred for routine 2D or transesophageal echocardiography (TEE)

Intervention

Live Three-Dimensional Echocardiography (L3D)

Comparator

Transthoracic echocardiography (2D) and transesophageal echocardiography (TEE)

Outcome

Visualization of the left atrial appendage (LAA)surrogate

Live 3D echocardiography significantly improves visualization of the left atrial appendage compared to 2D echocardiography and can accurately detect LAA thrombi when image quality is diagnostic.

Cite This Study

Agoston et al. (2006) studied this question.

synapsesocial.com/papers/6a736bc2644e61a44f4e5c00 https://doi.org/10.1111/j.1540-8175.2006.00181.x

Topics

Echocardiography Left atrial appendage closure

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Implication

L3D may improve LAA visualization in routine echocardiography; hypothesis-generating for thrombus detection, should not yet change practice.

Assessment of Left Atrial Appendage by Live Three‐Dimensional Echocardiography: Early Experience and Comparison with Transesophageal Echocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Assessment of Left Atrial Appendage by Live Three‐Dimensional Echocardiography: Early Experience and Comparison with Transesophageal Echocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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