Restoration of soft tissue defects is essential for periodontal and implant surgeries.Although autologous grafts remain the gold standard, they increase patient morbidity owing to donor site harvesting.This retrospective case series evaluated the porcine-derived collagen matrix as a less invasive alternative across three indications: vestibuloplasty, soft tissue augmentation, and alveolar ridge preservation (ARP).The xenogeneic matrix showed biocompatibility, favorable initial healing, and rapid epithelialization.The elimination of donor site surgery reduced patient morbidity.The matrix was integrated without notable complications, providing acceptable esthetic and functional contours for both open and closed healing.However, physical limitations including postoperative absorption, decreased tensile strength upon hydration, and rapid degradation were observed as a biomechanical trade-off.In conclusion, this matrix serves as a clinically feasible substitute for autogenous grafts, minimizing discomfort while achieving favorable outcomes.
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Song et al. (2026) studied this question.
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