This case report highlights the clinical challenge of managing thromboprophylaxis for atrial fibrillation in a patient with a bleeding disorder (hemophilia A).
Case of AF thromboprophylaxis in hemophilia carrier adds to sparse reports; leaves open optimal strategy pending controlled trials.
Nonvalvular atrial fibrillation (AF) is a common age-related arrthymia and a leading cause of stroke in the elderly; with an aging hemophilia population, the number of patients developing AF is increasing. There are no controlled trials on thromboprophylaxis in this group of patients, only consensus opinion was based on small case reports. We present a female patient, carrier for hemophilia and with clinically moderately severe hemophilia who developed FA. We discuss the literature with respect to this group of patients and current recommendations for thromboprophylaxis.
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Murray et al. (2018) studied this question.
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