Why the study?
Does captopril treatment reduce enhanced urinary albumin excretion in patients with congestive heart failure?
Population
13 patients with congestive heart failure (NYHA class II-IV) and 13 healthy control subjects
Comparison
Captopril treatment for 4 weeks vs Healthy control subjects and pre-treatment…
Design
Cohort
Follow-up
4 weeks
Authors
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Elevated albuminuria in heart failure persists after short-term captopril; leaves open its prognostic value and response to longer therapy.
Does captopril treatment reduce enhanced urinary albumin excretion in patients with congestive heart failure?
Patients with congestive heart failure have increased urinary albumin excretion correlated with plasma renin activity, which is not significantly altered by 4 weeks of captopril therapy.
Eiskjær et al. (1992) studied this question.
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