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March 1, 2020The American Journal of Sports Medicine

Blood Flow Restriction Training Applied With High-Intensity Exercise Does Not Improve Quadriceps Muscle Function After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial

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Why the study?

Current rehabilitation after ACLR often fails to restore quadriceps muscle strength, limiting return to play and increasing recurrent injury risk; whether BFRT with high-intensity exercise improves recovery of quadriceps muscle function is unclear.

Does blood flow restriction training with high-intensity exercise improve quadriceps muscle function in patients undergoing anterior cruciate ligament reconstruction?

Population

34 patients scheduled to undergo ACLR

Comparison

BFRT (concentric or eccentric) vs non-BFRT high-intensity exercise

Design

Randomized controlled trial

Authors

MCMichael T. CurranUniversity of MichiganABAsheesh BediWashington University in St. LouisCMChristopher L. MendiasHospital for Special Surgery

Discussion

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Implication

BFRT adds no benefit to high-intensity rehab after ACLR; challenges routine adoption and directs research toward protocol optimization or alternatives.

Structured PICO

Does blood flow restriction training with high-intensity exercise improve quadriceps muscle function in patients undergoing anterior cruciate ligament reconstruction?

P
Population
34 patients scheduled to undergo anterior cruciate ligament reconstruction (ACLR), mean age 16.5 years, 19 female.
I
Intervention
Blood flow restriction training (BFRT) with high-intensity exercise (single-leg isokinetic leg press at 70% 1-RM, 4 sets of 10 reps, 2 times per week for 8 weeks starting 10 weeks postoperatively, with cuff at 80% limb occlusion pressure) during either concentric or eccentric action.
C
Comparator
High-intensity exercise (concentric or eccentric) without blood flow restriction training.
O
Outcome
Change in isometric and isokinetic (60 deg/s) quadriceps peak torque, quadriceps muscle activation, and rectus femoris muscle volume from baseline to after BFRT and at return to activity.surrogate

Blood flow restriction training added to high-intensity exercise does not significantly improve quadriceps muscle strength, activation, or volume after anterior cruciate ligament reconstruction.

Cite This Study

Curran et al. (2020) studied this question.

synapsesocial.com/papers/6a73796499ee5b8bf26c355ahttps://doi.org/10.1177/0363546520904008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Exercise with Blood Flow Restriction to Improve Quadriceps Function Long After ACL Reconstruction2019 · 86 citations
  2. 2Intermittent blood flow restriction does not reduce atrophy following anterior cruciate ligament reconstruction2015 · 118 citations
  3. 3Progression Models in Resistance Training for Healthy Adults2009 · 4,305 citations
  4. 4Strength Training with Blood Flow Restriction Diminishes Myostatin Gene Expression2011 · 467 citations
  5. 5The Impact of Quadriceps Femoris Strength Asymmetry on Functional Performance at Return to Sport Following Anterior Cruciate Ligament Reconstruction2012 · 457 citations