Why the study?
Does selective COX-2 inhibition increase cardiovascular risk in patients treated for arthritic pain?
Does selective COX-2 inhibition increase cardiovascular risk in patients treated for arthritic pain?
This review highlights the potential cardiovascular risks associated with selective COX-2 inhibitors due to unbalanced prostaglandin inhibition.
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May warrant caution with selective COX-2 inhibitors in high-risk patients; leaves open net benefit versus traditional NSAIDs pending prospective trials.
Stacy et al. (2006) studied this question.
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