Why the study?
Does grand multiparity increase the risk of maternal and neonatal complications compared to second and third parae?
Population
Grand multiparous women (records from 1974-1983)
Comparison
Grand multiparity (exposure) vs Equally large control group consisting of second…
Design
Cohort
Authors
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May support closer monitoring in grand multipara pregnancies; leaves open independent causality after confounder adjustment.
Does grand multiparity increase the risk of maternal and neonatal complications compared to second and third parae?
Grand multiparity is associated with significantly increased perinatal mortality and neonatal morbidity compared to second and third pregnancies.
Tanbo et al. (1987) studied this question.
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