Population
82 patients with untreated essential hypertension, mean age 57.9, 60% male, based in Japan. Excluded…
Design
Cross-sectional
Follow-up
24-hour
Authors
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May implicate autonomic tone in morning BP elevation; hypothesis-generating and should not yet change practice.
Parasympathetic activation before waking and relative sympathetic activation around waking are independently correlated with morning blood pressure elevation in hypertensive patients.
Takagi et al. (2006) studied this question.
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