Why the study?
Is coronary atherosclerosis associated with impaired left ventricular function and chamber dilatation in patients with severe aortic stenosis?
Population
78 elderly patients with severe aortic stenosis and no previous myocardial infarction or regional wall…
Comparison
Presence of coronary atherosclerosis… vs Smooth coronary arteries (no CAD, n=18).
Design
Cross-sectional
Authors
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CAD presence signals higher LV impairment risk in severe AS; hypothesis-generating for whether revascularization alters remodeling.
Is coronary atherosclerosis associated with impaired left ventricular function and chamber dilatation in patients with severe aortic stenosis?
In elderly patients with severe aortic stenosis, the presence of both obstructive and nonobstructive coronary atherosclerosis is independently associated with left ventricular enlargement and systolic dysfunction.
Vekshtein et al. (1990) studied this question.
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