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February 1, 2025Cancer MedicineOpen Access

Cardiovascular Disease Risk Among Older Asian, Native Hawaiian, Pacific Islanders Lung Cancer Survivors

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Why the study?

There may be heterogeneity in lung cancer-related outcomes for Asian, Native Hawaiian, and Pacific Islanders, prompting investigation into cardiovascular disease risk disparities compared to Non-Hispanic White survivors.

Does cardiovascular disease risk differ between older Asian, Native Hawaiian, Pacific Islander (ANHPI) and Non-Hispanic White lung cancer survivors?

Population

3920 ANHPI and 11,760 NHW lung cancer patients aged 66 years and older

Comparison

ANHPI lung cancer patients and race/ethnicity subgroups vs NHW lung cancer patients

Design

Registry-based retrospective cohort study

Authors

YPYancen PanCCChun-Pin E. ChangRTRanda Tao

Discussion

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Member takes

Overview

Disparities in CVD risk among ANHPI lung cancer survivors warrant attention; leaves open whether ethnicity-specific prevention improves outcomes.

Structured PICO

Does cardiovascular disease risk differ between older Asian, Native Hawaiian, Pacific Islander (ANHPI) and Non-Hispanic White lung cancer survivors?

P
Population
15,680 lung cancer patients aged 66 years and older (3,920 Asian, Native Hawaiian, and Pacific Islanders [ANHPI] and 11,760 Non-Hispanic White [NHW]) from the SEER-Medicare registry (1999-2017)
I
Intervention
Asian, Native Hawaiian, and Pacific Islander (ANHPI) race/ethnicity
C
Comparator
Non-Hispanic White (NHW) race/ethnicity
O
Outcome
Incident cardiovascular disease (including heart failure and ischemic heart disease)hard clinical

Older ANHPI lung cancer survivors have a lower overall risk of incident heart failure and ischemic heart disease compared to NHW survivors, though risk varies significantly among ANHPI subgroups.

Cite This Study

Pan et al. (2025) studied this question.

synapsesocial.com/papers/6a7381157af34f94aaa72d33https://doi.org/10.1002/cam4.70702
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