What question did this study set out to answer?

To describe the clinical, electrocardiographic, echocardiographic, and hemodynamic characteristics of asymmetrical apical hypertrophy as a presentation of hypertrophic nonobstructive cardiomyopathy.

January 1, 1982Japanese Heart JournalOpen Access

A case of asymmetrical apical hypertrophy which is a form of hypertrophic nonobstructive cardiomyopathy with giant negative T-waves.

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Population

1 adult male, 22 years old, with apical hypertrophy, a form of hypertrophic nonobstructive cardiomyopathy…

Design

Case_report

Follow-up

10 months

Authors

ASAbdolhamid SheikhzadehSegeberger Kliniken PGP GhabussiUniversity College Hospital at Westmoreland Street

Discussion

Member takes

Implication

Single case expands apical HCM phenotype; hypothesis-generating and should not change practice.

Key Points

To describe the clinical, electrocardiographic, echocardiographic, and hemodynamic characteristics of asymmetrical apical hypertrophy as a presentation of hypertrophic nonobstructive cardiomyopathy.
Evaluated a patient presenting with chest pain using 12-lead electrocardiography (ECG), echocardiography, right anterior oblique left ventricular angiography, coronary angiography, and hemodynamic testing (N=1).
Assessed left ventricular outflow obstruction using an isoproterenol provocation challenge.
Electrocardiogram demonstrated giant negative T-waves reaching an amplitude of 4.0 mV.
Echocardiography and ventriculography demonstrated marked apical wall thickening of up to 40 mm, systolic anterior motion of the anterior mitral leaflet, elevated left ventricular end-diastolic pressure, and dilated coronary arteries.
Hemodynamic testing confirmed nonobstructive physiology with a negative isoproterenol provocation test.

Structured PICO

Population

1 adult male (n=1), 22 years old, with apical hypertrophy (AH), a form of hypertrophic nonobstructive cardiomyopathy (HNCM), presenting with chest pain and giant negative T-waves.

Outcome

Clinical, hemodynamic, electrocardiographic, echocardiographic, and angiographic findings of apical hypertrophysurrogate

This case report highlights that apical hypertrophy is a distinct morphological variant of hypertrophic cardiomyopathy characterized by giant negative T-waves and marked apical wall thickening without outflow obstruction.

Cite This Study

Sheikhzadeh et al. (1982) studied this question.

synapsesocial.com/papers/6a7392a55946a55bc0fb6cb4 https://doi.org/10.1536/ihj.23.843

Topics

Hypertrophic cardiomyopathy Echocardiography

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A case of asymmetrical apical hypertrophy which is a form of hypertrophic nonobstructive cardiomyopathy with giant negative T-waves.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

A case of asymmetrical apical hypertrophy which is a form of hypertrophic nonobstructive cardiomyopathy with giant negative T-waves.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Topics

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