November 19, 2009European Journal of Heart Failure

Depressive Symptoms and Outcomes in Patients with Heart Failure: Data from the COACH Study

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Why the study?

Do depressive symptoms increase the risk of death or heart failure readmission in patients hospitalized for heart failure?

Structured PICO

Do depressive symptoms increase the risk of death or heart failure readmission in patients hospitalized for heart failure?

Population

958 patients enrolled after hospitalization for heart failure, mean age 71 +/- 11 years, 37% female, NYHA class II (51%) or III/IV (49%), LVEF 33% +/- 14%, median BNP 454 pg/mL.

Intervention

Presence of depressive symptoms (CES-D score >=16) or severe depressive symptoms (CES-D score >=24)

Comparator

Absence of depressive symptoms or lower CES-D scores

Outcome

Composite of death or readmission for heart failure at 18 months follow-upcomposite

In patients hospitalized for heart failure, the presence of depressive symptoms is independently associated with an increased risk of mortality and heart failure readmission.

Discussion

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Implication

Depressive symptoms may flag higher-risk hospitalized HF patients; leaves open whether screening or treatment improves outcomes.

Cite This Study

Lesman‐Leegte et al. (2009) studied this question.

synapsesocial.com/papers/6a73a2add3d4e530dbfb728c https://doi.org/10.1093/eurjhf/hfp155

Topics

Heart failure hospitalization Heart failure HFrEF treatment

View Full Paper

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Depressive Symptoms and Outcomes in Patients with Heart Failure: Data from the COACH Study

Structured PICO

Discussion

Implication

Cite This Study

Topics

Depressive Symptoms and Outcomes in Patients with Heart Failure: Data from the COACH Study

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider