What Is Normal Blood Pressure? Comparison of Ambulatory Pressure Level and Variability In Patients With Normal or Abnormal Left Ventricular Geometry
Population
191 adults whose left ventricular geometry was classified by echocardiography
Comparison
Ambulatory blood pressure monitoring during the… vs Comparison across different left ventricular…
Design
Cross-sectional
Authors
Discussion
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Implication
May support refined ambulatory BP thresholds via LV geometry; hypothesis-generating and requires prospective validation.
Structured PICO
P
Population
191 adults whose left ventricular (LV) geometry was classified by echocardiography (120 normal LV geometry, 35 concentric LV remodeling, 15 concentric LV hypertrophy, 21 eccentric hypertrophy)
I
Intervention
Ambulatory blood pressure monitoring (ABPM) during the waking day, at work, at home, and during sleep
C
Comparator
Comparison across different left ventricular geometry groups (normal LV geometry, concentric LV remodeling, concentric LV hypertrophy, eccentric hypertrophy)
O
Outcome
Level and variability of ambulatory blood pressuresurrogate
Using left ventricular geometry as a reference standard suggests that awake ambulatory blood pressures below 139/86 mm Hg are normal, while those above 149/95 mm Hg are pathologic.
Limitations
- Verification of these conclusions is needed in larger series
- Verification needed with the use of additional measures of preclinical hypertensive disease
Cite This Study
Devereux et al. (1993) studied this question.