Population
Plasma samples for pharmacokinetic investigation in animals and man
Design
Other
Authors
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Supports low-level monitoring in renin inhibitor trials; leaves open routine clinical adoption pending further validation.
A new, simple direct micro-radioimmunoassay was developed for the renin inhibitor CGP 60536, enabling pharmacokinetic studies without organic solvent extraction.
Lefèvre et al. (2000) studied this question.
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