Why the study?
Is active renin present in the plasma of anephric humans, and does it respond to renin inhibition?
Population
7 bilaterally nephrectomized (BNX) patients and normal controls
Comparison
Various specimen collection and storage… vs Normal controls
Design
Cross-sectional
Authors
Loading...
May indicate extrarenal renin in anephric patients; hypothesis-generating and should not yet change practice.
Is active renin present in the plasma of anephric humans, and does it respond to renin inhibition?
Active renin is present in the plasma of anephric humans and functions normally in response to a renin inhibitor, indicating an extrarenal source of active renin.
Opsahl et al. (1993) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: