Why the study?
Does the local environment (muscular vs nonmuscular tissue) affect continuous disease-free survival in patients with soft tissue sarcomas of the extremities?
Population
32 patients with soft tissue sarcomas of the extremities treated between 1974 and 1978
Design
Cohort
Follow-up
minimum 48 months
Authors
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Muscular tumor location may worsen sarcoma prognosis; hypothesis-generating and requires prospective validation before practice change.
Does the local environment (muscular vs nonmuscular tissue) affect continuous disease-free survival in patients with soft tissue sarcomas of the extremities?
The biologic milieu (muscular vs nonmuscular tissue) in which a soft tissue sarcoma grows may significantly affect disease-free survival.
Thompson et al. (1984) studied this question.
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