Key result
Surgical resection of lymphatic metastases from soft tissue sarcoma resulted in an estimated 5-year survival of 57%, whereas all patients treated without surgery died within 30 months.
Why the study?
Does surgical resection of involved lymph nodes improve survival in patients with soft tissue sarcoma in an extremity and lymph node metastasis?
Population
1066 patients who had surgery for soft tissue sarcoma in an extremity, of which 39 developed lymph node…
Comparison
Surgical resection of involved lymph nodes vs Treatment without surgery
Design
Cohort
Follow-up
up to 5 years
Authors
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Nodal resection was associated with survival in this cohort; leaves open whether isolated metastases warrant reclassification beyond Stage IV.
Cohort (n=1,066)
Does surgical resection of involved lymph nodes improve survival in patients with soft tissue sarcoma in an extremity and lymph node metastasis?
Absolute Event Rate: 57% vs 0%
Surgical resection of lymphatic metastases from soft tissue sarcoma in an extremity is associated with long-term survival, suggesting a need to reevaluate staging for isolated nodal metastases.
Riad et al. (2004) conducted a cohort in Soft tissue sarcoma in an extremity (n=1,066). Surgical resection of involved lymph nodes vs. Treatment without surgery was evaluated on 5-year survival. Surgical resection of lymphatic metastases from soft tissue sarcoma resulted in an estimated 5-year survival of 57%, whereas all patients treated without surgery died within 30 months.
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