Why the study?
Does diet-induced weight loss reduce pericardial fat, and is this reduction associated with improvements in liver fat and insulin sensitivity in overweight women?
Population
30 overweight nondiabetic women (BMI 28.2-46.8 kg/m2, age 22-41 years)
Design
Cohort
Follow-up
14.2 ± 4 weeks
Authors
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Weight loss reduces PAT independently of liver fat or insulin sensitivity changes; leaves open causal role of PAT in metabolic disease.
Does diet-induced weight loss reduce pericardial fat, and is this reduction associated with improvements in liver fat and insulin sensitivity in overweight women?
While pericardial fat is cross-sectionally associated with visceral fat, liver fat, and insulin resistance, weight-loss-induced reductions in pericardial fat do not correlate with improvements in insulin sensitivity, suggesting a lack of causal relationship.
Bosy‐Westphal et al. (2010) studied this question.
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