July 1, 1995Diabetes
Diabetic Ketoacidosis in Obese African-Americans
Population
77 African-American subjects, comprising 35 obese patients with diabetic ketoacidosis, 22 obese patients…
Design
Cohort
Follow-up
12 weeks
Authors
Discussion
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Member takes
Implication
May support insulin discontinuation after acute DKA in obese patients; leaves open confirmation of a distinct T2D subset.
Structured PICO
P
Population
77 African-American subjects, comprising 35 obese patients with diabetic ketoacidosis (DKA), 22 obese patients with hyperglycemia, 10 lean patients with DKA, and 10 obese nondiabetic subjects.
O
Outcome
Indexes of insulin secretion (acute insulin response to glucose and glucagon) and insulin sensitivitysurrogate
Obese African-American patients presenting with DKA often have preserved beta-cell function and represent a subset of type II diabetes, as many can discontinue insulin therapy after the acute episode resolves.
Cite This Study
Umpierrez et al. (1995) studied this question.