Why the study?
Does early inhibition of the renal sympathetic nervous system attenuate the progression of CKD in 5 of 6 nephrectomized rats?
Does early inhibition of the renal sympathetic nervous system attenuate the progression of CKD in 5 of 6 nephrectomized rats?
Early augmentation of the renal sympathetic nervous system is closely related to the development of partial ablation-induced CKD in rats, and early intervention attenuates disease progression.
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Early sympathetic inhibition findings in this rat model warrant targeted human studies; does not support clinical adoption in CKD.
Kobuchi et al. (2013) studied this question.
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