Why the study?
Is advancing age associated with reduced arterial elasticity and endothelial dysfunction in healthy males?
Population
24 healthy male volunteers, divided into young (n=12) and elderly (n=12) groups.
Comparison
Advancing age (elderly group) vs Young group
Design
Cross-sectional
Authors
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Reduced arterial elasticity in elderly healthy males supports age-related vascular changes; leaves open causal links to endothelial dysfunction and outcomes.
Is advancing age associated with reduced arterial elasticity and endothelial dysfunction in healthy males?
Reduced arterial elasticity measured noninvasively by pulse wave analysis parallels impaired endothelium-dependent vasodilation associated with advancing age.
Jie Tao (2004) studied this question.
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