March 29, 2011EP EuropaceOpen Access

The natural history of carotid sinus syncope and the effect of cardiac pacing

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Why the study?

Does permanent cardiac pacing reduce syncope recurrence in patients with carotid sinus syncope?

Structured PICO

Does permanent cardiac pacing reduce syncope recurrence in patients with carotid sinus syncope?

Population

906 patients (305 untreated and 601 treated) with severe recurrent syncope due to carotid sinus syndrome (CSS), pooled from 12 studies.

Intervention

Permanent cardiac pacing (pacemaker implantation, including single-chamber VVI and dual-chamber modes).

Comparator

No pacing therapy (untreated control).

Outcome

Syncope recurrence.hard clinical

Limitations

Studies were largely heterogeneous regarding patient selection
Heterogeneity in duration and position of carotid sinus massage
Heterogeneity in criteria for identification of mixed forms
Different modes of pacing used (single- vs. dual-chamber)

Discussion

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Implication

Permanent cardiac pacing provides an estimated 75% reduction in syncope recurrence for patients with carotid sinus syndrome, supporting current guideline recommendations despite the lack of large randomized trials.

Cite This Study

Brignole et al. (2011) studied this question.

synapsesocial.com/papers/6a73c4fa6acfb9d2a78de657 https://doi.org/10.1093/europace/euq516

View Full Paper

Ask AI

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The natural history of carotid sinus syncope and the effect of cardiac pacing

Structured PICO

Limitations

Discussion

Implication

Cite This Study

The natural history of carotid sinus syncope and the effect of cardiac pacing

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Also Consider