Highlights the high prevalence and variability of moderate or severe tricuspid regurgitation in patients with severe left-sided valvular heart disease.
Tricuspid regurgitation (TR) is considered a public health crisis due to the large number of incident cases, its poor outcome, and its notable undertreatment. 1 One of the challenges in the diagnosis and management of TR is its heterogeneity, 2 with several different clinical contexts resulting in TR that may have significant clinical implications.Previous epidemiological data from the Olmsted County community (Minnesota, USA) demonstrated that the most common clinical context for moderate or severe TR, most generally functional TR, was left-sided valvular heart diseases (LVHD-TR), accounting for 46% of cases of TR diagnosed in the community.In the Verona area (Italy), similar results showed LVHD-TR as the most prevalent (39%) TR form across different clinical contexts. 2,3espite the predominance of LVHD-TR, information on the prevalence of clinically significant TR within each type of LVHD-TR and on its management remains limited by single-centre case series, 4,5 the small size of epidemiological studies and the frequent lack of precise definition of the exact type of LVHD.Recently, Dreyfus and colleagues 6 addressed the topic of LVHD-TR by assessing 6883 patients with severe native LVHD or previous left-sided valvular intervention using data derived from the prospective EURObservational Research Programme (EORP) Valvular Heart Disease (VHD) II survey. 7The authors focused specifically on severe LVHD, which was the main aim of the EORP VHD II survey, 7 and provided important new insights.First, the prevalence of moderate or severe TR among patients with severe LVHD is highly variable depending on LVHD type.Indeed,
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Benfari et al. (2024) studied this question.