This study provides a mathematical model to explain controversies in interpreting heart rate variability under various physiological and pharmacological conditions.
May clarify HRV interpretation under dual autonomic control; leaves open clinical translation pending validation.
The aim of the study presented was to develop a mathematical model that could demonstrate the characteristics of beat-to-beat fluctuations in heart rate under simultaneous sympathetic and vagal controls. By this model, we attempted to illustrate the relation between autonomic activity and HRV, and to explain those controversies in interpreting HRV under certain physiological and pharmacological conditions.
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Chiu et al. (2001) studied this question.
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