Why the study?
Do biomarkers of inflammation and collagen turnover predict atrial fibrillation recurrence in patients undergoing catheter ablation for drug-resistant AF?
Population
50 patients who underwent catheter ablation for drug-resistant atrial fibrillation (AF)
Comparison
Measurement of biomarkers of inflammation and… vs Patients without AF recurrence
Design
Cohort
Follow-up
14.0 (4.7-20.9) months
Authors
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May aid pre-ablation risk stratification in drug-resistant AF; extends observational evidence on MMP-2 but warrants prospective validation.
Do biomarkers of inflammation and collagen turnover predict atrial fibrillation recurrence in patients undergoing catheter ablation for drug-resistant AF?
Elevated markers of collagen turnover, particularly MMP-2, independently predict atrial fibrillation recurrence after catheter ablation, highlighting the role of extracellular matrix remodeling in post-ablation outcomes.
Okumura et al. (2011) studied this question.
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