Population
Calmodulin complexed with an enzymatically active truncation mutant of skeletal muscle myosin light chain…
Design
Preclinical
Authors
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Provides first structural mechanism of CaM-MLCK activation; leaves open translation to human cardiovascular models.
The study provides the first structural view of Calmodulin complexed with a functional enzyme, revealing the mechanism of enzyme activation via conformational changes.
Krueger et al. (1997) studied this question.
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