Why the study?
Do tricyclic antidepressants increase the risk of proarrhythmia and death in patients with ischaemic heart disease?
Population
Elderly patients and patients with ischaemic heart disease or myocardial infarction
Design
Review
Authors
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Tricyclic antidepressants may carry a significant proarrhythmic risk and increase mortality in patients with ischaemic heart disease, similar to the risks observed with class I antiarrhythmic drugs.
Do tricyclic antidepressants increase the risk of proarrhythmia and death in patients with ischaemic heart disease?
Tricyclic antidepressants may carry a significant proarrhythmic risk and increase mortality in patients with ischaemic heart disease, similar to the risks observed with class I antiarrhythmic drugs.
Glassman et al. (2009) studied this question.
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