Why the study?
Do tricyclic antidepressants reduce sudden death in depressed patients with preexisting arrhythmias or post-myocardial infarction?
Population
Depressed patients with preexisting arrhythmias or post-myocardial infarction
Design
Editorial
Authors
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May warrant caution with TCAs post-MI; leaves open net benefit in depressed patients pending randomized data.
Do tricyclic antidepressants reduce sudden death in depressed patients with preexisting arrhythmias or post-myocardial infarction?
The safety of tricyclic antidepressants in cardiac patients is reconsidered, highlighting that their class I antiarrhythmic-like effects may not be beneficial post-myocardial infarction.
Alexander H. Glassman (1993) studied this question.
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