Why the study?
Do tricyclic antidepressants cause dose-related cardiotoxicity in children and adults?
Population
Children and adults receiving tricyclic antidepressants (e.g., imipramine hydrochloride)
Design
Review
Authors
Loading...
Supports dose-dependent TCA cardiotoxicity caution; leaves open precise contemporary risk estimates and monitoring thresholds.
Do tricyclic antidepressants cause dose-related cardiotoxicity in children and adults?
Tricyclic antidepressants can cause dose-related cardiotoxicity, including arrhythmias and sudden death, prompting caution against using higher-than-recommended dosages.
Donald S. Robinson (1976) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: