Why the study?
Does iNOS deletion attenuate cardiac remodeling and dysfunction in mice with heart failure post-myocardial infarction?
Does iNOS deletion attenuate cardiac remodeling and dysfunction in mice with heart failure post-myocardial infarction?
Lack of iNOS improves cardiac reserve and attenuates remodeling post-myocardial infarction in mice, partly by decreasing oxidative stress.
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iNOS deletion attenuates post-MI remodeling in mice; leaves open whether iNOS inhibition benefits human HF.
Liu et al. (2005) studied this question.
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