Why the study?
Does an antimicrobial prophylaxis regimen prevent primary wound infection in neurosurgical patients?
Does an antimicrobial prophylaxis regimen prevent primary wound infection in neurosurgical patients?
An antimicrobial prophylaxis regimen was associated with zero primary wound infections in 2000 consecutive major neurosurgical operations.
Antimicrobial prophylaxis was associated with zero infections in 2000 cases; hypothesis-generating and requires randomized confirmation before practice change.
Two neurosurgeons in private practice at three community hospitals followed a regimen of antimicrobial prophylaxis for 10 years. No primary wound infection occurred in a series of 2000 consecutive major operations. The study gives rise to certain recommendations for the prevention of postoperative sepsis in neurosurgical patients.
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Savitz et al. (1986) studied this question.
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