Why the study?
Does metoprolol reduce QTc intervals in survivors of acute myocardial infarction below 70 years of age?
Population
111 survivors of acute myocardial infarction below 70 years of age
Comparison
Metoprolol 100 mg b.i.d. vs Placebo
Design
RCT, Stratified by age, infarction size and ventricular arrhythmias and…
Follow-up
1 year
Authors
Loading...
Supports metoprolol for QTc shortening in post-MI survivors; confirms beta-blocker effects on repolarization.
Does metoprolol reduce QTc intervals in survivors of acute myocardial infarction below 70 years of age?
Metoprolol significantly shortens the QTc interval in survivors of acute myocardial infarction, particularly in those with prolonged QTc at discharge.
Ahnve et al. (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: