Population
Human embryonic kidney (HEK293) cells
Comparison
Pharmacological agents and serum-free medium… vs Heterologously expressed chimeric L-type calcium…
Design
Preclinical
Authors
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Endogenous currents in HEK293 cells may confound L-type expression studies; leaves open optimal controls for heterologous systems.
HEK293 cells possess endogenous calcium channel currents with distinct kinetic and pharmacological properties compared to heterologously expressed L-type calcium channels, which is important to consider when using these cells as expression systems.
Berjukow et al. (1996) studied this question.
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