Population
Murine genome (BALB/c mice and WEHI-3 cell line)
Design
Preclinical
Authors
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No direct clinical implications for cytokine therapies; leaves open the functional impact of nearby genomic alterations in murine IL-3.
The study determined the nucleotide sequence and genomic structure of the murine IL-3 gene, revealing identical primary structures between normal mice and a tumorigenic cell line.
Campbell et al. (1985) studied this question.
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