Why the study?
Does atropine sulfate affect heart rate differently in hyperthyroid versus euthyroid subjects?
Population
12 subjects (6 hyperthyroid and 6 euthyroid)
Comparison
Atropine sulfate vs Euthyroid subjects
Design
Other
Authors
Loading...
Supports vagal impairment in hyperthyroid tachycardia; leaves open relevance to atropine dosing or autonomic therapies.
Does atropine sulfate affect heart rate differently in hyperthyroid versus euthyroid subjects?
The resting tachycardia of hyperthyroidism is likely due to a combination of a direct rate-increasing effect of thyroxine on the sinoatrial node and an impairment of vagal inhibition.
David M. Heimbach (1972) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: