Why the study?
Does a comprehensive risk factor modification program improve ultrasound-assessed far-wall common carotid intima-media thickness or plaques in high-risk hypertensive patients?
Population
164 high-risk hypertensive patients
Comparison
Comprehensive risk factor modification program vs Usual care
Design
RCT, Randomized
Follow-up
3.5 years
Authors
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Comprehensive risk factor modification does not improve carotid measures despite better risk factors; challenges CIMT responsiveness as a surrogate in hypertension trials.
Does a comprehensive risk factor modification program improve ultrasound-assessed far-wall common carotid intima-media thickness or plaques in high-risk hypertensive patients?
A comprehensive nonpharmacological risk factor modification program in high-risk hypertensive patients did not improve carotid intima-media thickness or plaque status over 3.5 years despite improving individual risk factors.
Suurküla et al. (1996) studied this question.
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