December 1, 1997The Anatomical RecordOpen Access

Expression of the smooth-muscle proteins α-smooth-muscle actin and calponin, and of the intermediate filament protein desmin are parameters of cardiomyocyte maturation in the prenatal rat heart

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Population

Prenatal and neonatal Wistar rats

Design

Preclinical

Authors

YJYa JingBeijing University of Technology MMMarry MarkmanAmsterdam UMC Location University of Amsterdam GWGerry T. M. WagenaarTissue Dynamics (Israel)

Discussion

Member takes

Implication

No clinical implications yet; leaves open validation of these markers for modeling cardiomyocyte maturation in translational research.

Structured PICO

Population

Prenatal and neonatal Wistar rats

Intervention

Immunohistochemical staining for alpha- and beta-MHC, alpha-SMA, calponin, and desmin

Outcome

Spatiotemporal expression pattern of alpha-SMA, calponin, and desmin during cardiomyocyte maturationsurrogate

Alpha-SMA, calponin, and desmin exhibit distinct spatiotemporal expression patterns during rat heart development, serving as markers for regional cardiomyocyte maturation.

Cite This Study

Jing et al. (1997) studied this question.

synapsesocial.com/papers/6a743b32f40cdade3da7f8f6 https://doi.org/10.1002/(sici)1097-0185(199712)249:4<495::aid-ar9>3.0.co;2-q

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Expression of the smooth-muscle proteins α-smooth-muscle actin and calponin, and of the intermediate filament protein desmin are parameters of cardiomyocyte maturation in the prenatal rat heart

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Expression of the smooth-muscle proteins α-smooth-muscle actin and calponin, and of the intermediate filament protein desmin are parameters of cardiomyocyte maturation in the prenatal rat heart

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider