January 1, 1990IEEE Transactions on Biomedical Engineering

Design and control of the atrio-aortic left ventricular assist device based on O/sub 2/ consumption

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Population

Closed-loop analog model of the normal and impaired heart, vascular system, and left ventricular assist device

Design

Preclinical

Authors

GDGary DrzewieckiRutgers, The State University of New Jersey JPJames J. PillaUniversity of Pennsylvania WWW. WelkowitzRutgers, The State University of New Jersey

Discussion

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Implication

May reduce myocardial oxygen consumption with optimized LVAD timing; leaves open translation from animal models to clinical use.

Structured PICO

Population

Closed-loop analog model of the normal and impaired heart, vascular system, and left ventricular assist device (LVAD)

Intervention

Adjustment of LVAD timing and control variables (pump ejection timing, filling pressure, ejection pressure)

Outcome

Heart oxygen consumption (computed via pressure-volume-area method)surrogate

Computational modeling suggests that synchronous LVAD pumping with ejection starting immediately after aortic valve closure optimizes myocardial oxygen consumption.

Cite This Study

Drzewiecki et al. (1990) studied this question.

synapsesocial.com/papers/6a7447b04f499509b5db5ce0 https://doi.org/10.1109/10.46252

Topics

Mechanical circulatory support

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Design and control of the atrio-aortic left ventricular assist device based on O/sub 2/ consumption

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Design and control of the atrio-aortic left ventricular assist device based on O/sub 2/ consumption

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider