Why the study?
Does enterovirus-related diarrhoea increase the risk of severe complications in children with hand, foot and mouth disease and herpangina?
Population
804 inpatients with hand, foot and mouth disease or herpangina admitted to the Paediatric Department of…
Comparison
Presence of enterovirus-related diarrhoea vs Absence of diarrhoea
Design
Cohort
Authors
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Diarrhoea in HFMD/HA may flag higher organ-injury risk; leaves open causal impact and need for prospective trials.
Does enterovirus-related diarrhoea increase the risk of severe complications in children with hand, foot and mouth disease and herpangina?
Enterovirus-related diarrhoea in children with HFMD/HA is associated with a significantly higher risk of multi-organ dysfunction, hepatic injury, and myocardial injury.
Zhou et al. (2016) studied this question.
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