Why the study?
Does the VP1 RT-snPCR assay improve the detection and identification of enterovirus serotypes in clinical specimens compared to the 5' nontranslated region RT-snPCR assay?
Population
Clinical specimens and prototype enterovirus strains
Comparison
VP1 reverse transcription-seminested PCR assay vs In-house EV 5' nontranslated region RT-snPCR assay
Design
Other
Authors
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May aid EV detection across serotypes in specimens; leaves open superiority to 5'NTR assays pending comparative validation.
Does the VP1 RT-snPCR assay improve the detection and identification of enterovirus serotypes in clinical specimens compared to the 5' nontranslated region RT-snPCR assay?
The developed VP1 RT-snPCR assay provides a sensitive method for direct detection and unambiguous identification of all enterovirus serotypes from clinical specimens.
Nix et al. (2006) studied this question.
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