Why the study?
What are the prescribing patterns of antihypertensive drugs and their adherence to JNC7 guidelines in a tertiary care hospital in Bangalore?
What are the prescribing patterns of antihypertensive drugs and their adherence to JNC7 guidelines in a tertiary care hospital in Bangalore?
In a tertiary care hospital in Bangalore, ARBs and CCBs were the most frequently prescribed antihypertensives, with prescribing patterns partly in accordance with JNC VII guidelines.
Patterns partly align with JNC7 in this single-center cohort; leaves open generalizability and outcome impact.
BACKGROUND: Hypertension is the most common cardiovascular disease. Sustained arterial hypertension damages blood vessels in kidney, heart, brain and leads to an increased incidence of renal failure, coronary disease, heart failure and stroke. Effective pharmacologic lowering of blood pressure has been shown to prevent damage to blood vessel and so substantially reduce morbidity and mortality rates.AIM: This drug utilization study was intended to find out the preferred drug group prescribed either alone or in combinations and their adherence to the JNC7 guidelines. Furthermore the prescription variations as regards to the age and concomitant illness were also analyzed. METHODS AND MATERIAL: Drug utilization data were analyzed after getting the patient's particulars regarding age, sex, drugs, concomitant illness etc. in the proforma. RESULTS: After analysis, it was found that most frequently prescribed antihypertensive drugs were ARBs (58%), CCBs (50%), Beta blockers(15%), Diuretics (14%). 68% received monotherapy while remaining 32% received combination therapy. CONCLUSION: The prescription pattern was found to be partly in accordance with JNC VII guidelines.
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Kalamdani et al. (2013) studied this question.
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