Key result
Among 250 adult hypertensive patients on treatment, calcium channel blockers were the most commonly prescribed class (42.8%), and the JNC-8 recommended target blood pressure was achieved in 49.6% of patients.
Why the study?
Evaluating antihypertensive drug utilization and the prevalence of blood pressure control may help reduce the burden of hypertension and related health expenditures.
Cross-Sectional (n=250)
No
While antihypertensive prescription patterns in this Indian tertiary care hospital largely align with JNC-VIII guidelines, target blood pressure is achieved in less than half of the treated patients.
BP control achieved in <50% despite CCB predominance; leaves open barriers to target attainment in real-world Indian cohorts.
Background: Hypertension is a major independent risk factor for coronary artery disease, congestive heart failure, stroke, chronic kidney disease and peripheral vascular diseases if left untreated. Drug utilization study of antihypertensive drugs and the study on prevalence of blood pressure control would help in reducing the burden of the disease and health expenditure.Methods: The study was conducted in the Outpatient Department of Medicine in Government Medical College, Thrissur. Patients aged 18yrs or above diagnosed with hypertension, on antihypertensive drugs were enrolled in the study. Patients suffering from secondary hypertension and acutely ill were excluded. Patients were enrolled after taking an informed consent. Demographic data, present treatment for hypertension, associated co- morbid conditions if any, and treatment of the same were recorded. BP was recorded, and cost of treatment was calculated using CIMS.Results: A total of 250 patients were included in the study. Mono therapy was used in 64.8% patients and combination therapy in 35.2%. Overall drug utilization pattern showed that CCBs (42.8%) were most commonly prescribed, followed by ACEIs (32.4%) and ARBs (29.2%). Most commonly prescribed combination therapy was ACE I + BB (29.3%), followed by ARB + CCB (21.3%). Mean cost of antihypertensive drug therapy was 3057.8 Rs / yr. Recommended target BP was achieved in 49.6% of patients.Conclusions: The prescription pattern of antihypertensive drug was in accordance to the JNC-VIII guidelines. The blood pressure target was achieved only in less than 50% of patients.
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Ramadas et al. (2019) conducted a cross-sectional in Hypertension (n=250). Antihypertensive drugs was evaluated on Prevalence of blood pressure control based on JNC-8 guidelines. Among 250 adult hypertensive patients on treatment, calcium channel blockers were the most commonly prescribed class (42.8%), and the JNC-8 recommended target blood pressure was achieved in 49.6% of patients.
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