Key result
Older age was associated with a larger notch relative amplitude (p=0.016), and female gender with increased timing of the reflected wave (p<0.02) in photoplethysmographic pulses of young adults.
Why the study?
Does contour analysis of the photoplethysmographic dicrotic notch identify differences in arterial stiffness by age and gender in young adults?
Cross-Sectional (n=15)
Does contour analysis of the photoplethysmographic dicrotic notch identify differences in arterial stiffness by age and gender in young adults?
p-value: p=0.016
Analysis of the photoplethysmographic dicrotic notch can non-invasively detect differences in arterial stiffness related to age and gender in young adults.
PPG notch analysis may detect early age- and gender-related stiffness differences in young adults; hypothesis-generating and requires prospective validation.
This study aims to investigate arterial stiffness in selected young adults by non-invasively determining the characteristics of the photoplethysmographic dicrotic notch. A total of 15 volunteers participated in this study, divided into four groups by age and gender. Contour analysis was applied to analyse the photoplethysmographic dicrotic notch, including time-related and height-related parameters. The height of reflected wave, mirrored by the notch relative amplitude (NRA), was found to be significantly larger in the older group compared to the younger group (p = 0.016). The timing of the reflected wave, measured by three parameters, i.e. notch index (NI), notch latency (NL) and peak-to-notch latency (PTNL), significantly increased in the female group compared to the male group (all p < 0.02). The results confirm that arterial stiffness occurs in young adults, and demonstrate that a difference of arterial stiffness exists between young male and female. This study indicates that examining the characteristic notch of the PPG pulse could help in identifying differences of vascular activities.
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Shi et al. (2009) conducted a cross-sectional in Arterial stiffness (n=15). Older age and female gender vs. Younger age and male gender was evaluated on Photoplethysmographic dicrotic notch characteristics (notch relative amplitude and timing parameters) (p=0.016). Older age was associated with a larger notch relative amplitude (p=0.016), and female gender with increased timing of the reflected wave (p<0.02) in photoplethysmographic pulses of young adults.
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