Why the study?
Loop diuretics are the primary treatment for congestion in acutely decompensated heart failure, but diuretic resistance necessitates adjuvant diuretic therapies.
This review summarizes the pharmacological modalities for managing congestion and diuretic resistance in heart failure, emphasizing the emerging roles of SGLT2 inhibitors and sacubitril/valsartan alongside traditional diuretics.
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Adjuvant diuretic options may help resolve resistant congestion; leaves open optimal regimens pending randomized data.
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Piardi et al. (2021) conducted a review in Heart failure with congestion. Diuretics and adjuvant therapies was evaluated.
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