Key result
Angiographic collaterals during STEMI increased from 19% at 0-6 h to 68% at >14 days (p<0.001), with preinfarction angina being the only independent determinant (OR 3.1; 95% CI 1.2-8.5).
Why the study?
Does the time from symptom onset to angiography affect the appearance of coronary collaterals in patients with STEMI?
Observational (n=187)
Does the time from symptom onset to angiography affect the appearance of coronary collaterals in patients with STEMI?
Coronary collaterals become increasingly apparent over time following acute coronary occlusion in STEMI, with preinfarction angina being a strong predictor of their early appearance.
Answers are grounded in this paper and cite their sources.
Collateral visualization rises with time to angiography in STEMI; leaves open whether preinfarction angina affects outcomes or warrants prospective trials.
Objective: The appearance of collaterals during ST-elevation myocardial infarction (STEMI) and clinical factors potentially associated with their early appearance were studied. Background: The appearance of collaterals is associated with the duration of chronic coronary occlusion. Nevertheless, the question remains as to whether collaterals are already apparent shortly after an acute coronary occlusion. Results: The appearance of collaterals was studied during STEMI, in 187 patients who underwent angiography at various times after the onset of symptoms. For the onset-to-angiography groups of 0–6 h, >6–9 h, >9–24 h, >1–7 days, >7–14 days and >14 days, the prevalence of angiographic collaterals (Rentrop classification 2–3) were 19, 31, 41, 40, 50 and 68%, respectively (p < 0.001). Among the clinical factors, preinfarction angina was the only independent determinant (odds ratio 3.1; 95% CI: 1.2–8.5). Conclusion: As in chronic coronary occlusion, after acute occlusion the appearance of angiographic visible co...
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Ng et al. (2012) conducted an observational in ST-elevation myocardial infarction (STEMI) (n=187). Time from symptom onset to angiography and preinfarction angina was evaluated on Prevalence of angiographic collaterals (Rentrop classification 2-3) (OR 3.1, 95% CI 1.2-8.5, p=<0.001). Angiographic collaterals during STEMI increased from 19% at 0-6 h to 68% at >14 days (p<0.001), with preinfarction angina being the only independent determinant (OR 3.1; 95% CI 1.2-8.5).
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