Key result
Older age was an independent predictor of medication underuse (OR 1.05 per year), with 51.5% of older patients not taking any recommended medications compared to 30.7% of younger patients.
Why the study?
Does older age and associated socio-demographic factors increase the underuse of recommended secondary prevention medications in ACS patients at least one year after discharge?
Observational (n=469)
No
Does older age and associated socio-demographic factors increase the underuse of recommended secondary prevention medications in ACS patients at least one year after discharge?
Odds Ratio: 1.05 (95% CI 1.02–1.08)
Absolute Event Rate: 51.5% vs 30.7%
p-value: p=0.002
Older ACS patients are significantly more likely to underuse secondary prevention medications due to polypharmacy and low education, whereas younger patients underuse them primarily due to cost and depression.
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May support age-specific adherence monitoring in ACS; leaves open causal factors and intervention effects.
Jin et al. (2014) conducted an observational in Acute coronary syndrome (n=469). Older age (≥65 years) vs. Younger age (<65 years) was evaluated on Underuse of recommended medications (OR 1.05, 95% CI 1.02-1.08, p=0.002). Older age was an independent predictor of medication underuse (OR 1.05 per year), with 51.5% of older patients not taking any recommended medications compared to 30.7% of younger patients.
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