Population
Isolated human, cat, and guinea pig ventricular myocytes
Design
Preclinical
Authors
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Does not alter clinical practice; extends Gi-mediated IK(ACh) activation to ventricular myocytes in mammals.
This study demonstrates that acetylcholine directly activates muscarinic K+ channels in mammalian ventricular myocytes via the Gi protein, expanding our understanding of parasympathetic regulation in the ventricle.
Koumi et al. (1994) studied this question.
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