Population
Cat atrial myocytes
Comparison
Two consecutive exposures to acetylcholine… vs First ACh exposure, or absence of specific…
Design
Preclinical
Authors
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Preclinical findings in feline myocytes warrant no clinical changes; extends mechanistic understanding of atrial K+ regulation but leaves translation open.
Acetylcholine activates a glibenclamide-sensitive K+ current in cat atrial myocytes through a mechanism involving M1 muscarinic receptors, intracellular Ca2+, and protein kinase C.
Wang et al. (1995) studied this question.
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