Key result
Nicorandil can induce colovesical fistulas and severe ulcers, particularly in patients with underlying diverticular disease.
Highlights the importance of medication reviews for nicorandil in patients presenting with ulcer or fistula symptoms, particularly those with diverticular disease.
Alerts to nicorandil fistulas in diverticular disease; leaves open need for prospective confirmation.
Nicorandil's adverse effects can cause severe patient morbidity and can present to any specialty. Those with underlying diverticular disease are most susceptible. Medication reviews are vital for patients presenting with ulcer or fistula symptoms.
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Noyes et al. (2021) studied this question. Nicorandil can induce colovesical fistulas and severe ulcers, particularly in patients with underlying diverticular disease.
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