Key result
Whole-heart flow-sensitive 4D MRI successfully demonstrated regional flow alterations, such as poststenotic helix formation and asymmetric flow distributions, in a complex single ventricle case.
Why the study?
Does whole-heart flow-sensitive 4D MRI demonstrate regional flow alterations in a pediatric patient with complex congenital heart disease?
Case Report (n=1)
Does whole-heart flow-sensitive 4D MRI demonstrate regional flow alterations in a pediatric patient with complex congenital heart disease?
Flow-sensitive 4D MRI can noninvasively evaluate complex 3D hemodynamics in pediatric patients with repaired congenital heart disease without radiation exposure.
4D MRI feasible for regional flow mapping in single ventricle; extends technical application but leaves open validation before clinical use.
We report the comprehensive evaluation of the complex hemodynamics in a rare case of a pediatric patient after repair of congenital heart disease with multiple abnormalities including hypoplastic left heart, double outlet right ventricle, transposition of great arteries, ventricular septal defect, aortic coarctation, and total cavopulmonary connection. Based on a single measurement, whole-heart flow-sensitive 4D magnetic resonance imaging (MRI) was able to demonstrate a number of regional flow alterations such as poststenotic helix formation and asymmetric flow distributions for the double arterial outlet and to the left and right lungs. Our findings illustrate the potential role of flow-sensitive 4D MRI as a noninvasive and radiation-free technique for the frequent postinterventional follow-up in these pediatric patients.
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Markl et al. (2012) conducted a case report in Congenital heart disease with multiple abnormalities (single ventricle physiology) (n=1). Whole-heart flow-sensitive 4D magnetic resonance imaging (MRI) was evaluated on Regional flow alterations. Whole-heart flow-sensitive 4D MRI successfully demonstrated regional flow alterations, such as poststenotic helix formation and asymmetric flow distributions, in a complex single ventricle case.
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